Bupivacaine Solution

Pronunciation: byoo-PIV-a-kane
Generic Name: Bupivacaine
Brand Name: Examples include Marcaine and Sensorcaine

Bupivacaine Solution is used for:

Numbing (loss of feeling) during dental or surgical procedures, labor, or delivery. It may also be used for other conditions as determined by your doctor.

Bupivacaine Solution is a local anesthetic. It works by blocking the generation and conduction of nerve impulses.

Do NOT use Bupivacaine Solution if:

• you are allergic to any ingredient in Bupivacaine Solution or other similar medicines (eg, amide-type anesthetics)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Bupivacaine Solution:

Some medical conditions may interact with Bupivacaine Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver or kidney problems, heart disease, or blood pressure problems

Some MEDICINES MAY INTERACT with Bupivacaine Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, atenolol) or digoxin because the risk of side effects such as abnormal heartbeat may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bupivacaine Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bupivacaine Solution:

Use Bupivacaine Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Bupivacaine Solution will be administered as an injection at your doctor's office, hospital, or clinic.


• If you miss a dose of Bupivacaine Solution, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Bupivacaine Solution.

Important safety information:

• Bupivacaine Solution may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Bupivacaine Solution. Using Bupivacaine Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• If you are going home before the numbness wears off, protect the treated area from injury until you regain feeling. If you received Bupivacaine Solution for a dental procedure, do not chew gum or eat until the feeling comes back. Also be careful not to bite your tongue or the inside of your mouth.


• Some of these products contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your pharmacist to determine if the product you are taking contains sulfites.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Bupivacaine Solution during pregnancy. Bupivacaine Solution is excreted in breast milk. Do not breast-feed while taking Bupivacaine Solution.

Possible side effects of Bupivacaine Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild dizziness or drowsiness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; changes in hearing; chest pain; excitement; irregular heartbeat; nausea; numbness that lasts for more than a few hours; restlessness; ringing in the ears; seizures; severe dizziness or drowsiness; tremors; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include seizures; shortness of breath; slow heartbeat.

Proper storage of Bupivacaine Solution:

Store Bupivacaine Solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Bupivacaine Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Bupivacaine Solution, please talk with your doctor, pharmacist, or other health care provider.


• Bupivacaine Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bupivacaine Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bupivacaine resources

• Bupivacaine Use in Pregnancy & Breastfeeding
• Bupivacaine Drug Interactions
• Bupivacaine Support Group
• 2 Reviews for Bupivacaine - Add your own review/rating

Compare Bupivacaine with other medications

• Cesarean Section
• Local Anesthesia
• Postoperative Pain

Bromazep

Bromazep may be available in the countries listed below.

Ingredient matches for Bromazep

Bromazepam

Bromazepam is reported as an ingredient of Bromazep in the following countries:

• Bangladesh

International Drug Name Search

Casanmil S

Casanmil S may be available in the countries listed below.

Ingredient matches for Casanmil S

Nifedipine

Nifedipine is reported as an ingredient of Casanmil S in the following countries:

• Japan

International Drug Name Search

Bicarbonato Sod Grifols

Bicarbonato Sod Grifols may be available in the countries listed below.

Ingredient matches for Bicarbonato Sod Grifols

Sodium Bicarbonate

Sodium Bicarbonate is reported as an ingredient of Bicarbonato Sod Grifols in the following countries:

• Spain

International Drug Name Search

Merocef

Merocef may be available in the countries listed below.

Ingredient matches for Merocef

Meropenem

Meropenem is reported as an ingredient of Merocef in the following countries:

• Indonesia

International Drug Name Search

Didronel

Generic Name: etidronate (e ti DROE nate)

Brand Names: Didronel

What is etidronate?

Etidronate is in a group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body.

Etidronate is used to treat Paget's disease, and to treat conditions of irregular bone growth due to hip fracture or spinal cord injury.

Etidronate may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about etidronate?

Take etidronate with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking an etidronate tablet. For at least the first 2 hours after taking etidronate, do not eat or drink anything other than plain water, and do not take any other medicines including vitamins or mineral supplements.

Especially avoid drinking milk or eating dairy products within 2 hours after taking etidronate. Also avoid taking supplements that contain calcium, magnesium, iron, or aluminum (such as in multivitamins with iron, and in many types of antacids).

Some people using medicines similar to etidronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using etidronate. You may need to stop using the medicine for a short time.

Talk with your doctor about the risks and benefits of using this medication.

What should I discuss with my healthcare provider before taking etidronate?

Do not take etidronate if you have a condition called osteomalacia (softening of the bones), or a problem with the movement of muscles in your esophagus.

If you have any of these other conditions, you may need a dose adjustment or special tests:

• 
  

  diarrhea;

  
  


• 
  

  a bone fracture;

  
  


• 
  

  trouble swallowing;

  
  


• 
  

  a stomach or esophageal ulcer or disease; or

  
  


• kidney disease.

Some people using medicines similar to etidronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.

You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and dental surgery or pre-existing dental problems.

Talk with your doctor about the risks and benefits of using this medication.

FDA pregnancy category C. It is not known whether etidronate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.. It is not known whether etidronate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take etidronate?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not crush, chew, or suck the pill. Swallow it whole. Take each etidronate tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking an etidronate tablet. For at least the first 2 hours after taking etidronate, do not eat or drink anything other than plain water, and do not take any other medicines including vitamins or mineral supplements.

It is important to take etidronate regularly to get the most benefit.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using etidronate. You may need to stop using the medicine for a short time.

After you stop taking etidronate, you must stay off the medication for at least 90 days before starting etidronate therapy again.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Etidronate is only part of a complete program of treatment that may also include taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

See also: Didronel dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include vomiting, numbness or tingly feeling around your mouth, fast or slow heart rate, muscle tightness or contraction, overactive reflexes.

What should I avoid while taking etidronate?

Avoid drinking milk or eating dairy products within 2 hours after taking etidronate. Also avoid taking supplements that contain calcium, magnesium, iron, or aluminum (such as in multivitamins with iron, and in many types of antacids).

Etidronate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using etidronate and call your doctor at once if you have any of these serious side effects:

• 
  

  painful or difficult swallowing;

  
  


• 
  

  severe heartburn, burning pain in your upper stomach, or coughing up blood;

  
  


• 
  

  severe joint, bone, or muscle pain;

  
  


• 
  

  jaw pain, numbness, or swelling;

  
  


• 
  

  severe diarrhea;

  
  


• 
  

  bone fracture; or

  
  


• 
  

  a red, blistering, peeling skin rash.

  
  

Less serious side effects may include:

• 
  

  mild diarrhea;

  
  


• 
  

  headache, confusion;

  
  


• 
  

  muscle cramps, joint pain; or

  
  


• 
  

  numbness or tingly feeling.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect etidronate?

Before taking etidronate, tell your doctor if you are taking a blood thinner such as warfarin (Coumadin, Jantoven).

This list is not complete and other drugs may interact with etidronate. Tell your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Didronel resources

• Didronel Side Effects (in more detail)
• Didronel Dosage
• Didronel Use in Pregnancy & Breastfeeding
• Drug Images
• Didronel Drug Interactions
• Didronel Support Group
• 0 Reviews for Didronel - Add your own review/rating

• Didronel Prescribing Information (FDA)


• Didronel Monograph (AHFS DI)


• Didronel Advanced Consumer (Micromedex) - Includes Dosage Information


• Didronel Consumer Overview


• Didronel MedFacts Consumer Leaflet (Wolters Kluwer)


• Etidronate Prescribing Information (FDA)

Compare Didronel with other medications

• Heterotopic Ossification, Spinal Cord Injury
• Heterotopic Ossification, Total Hip Arthroplasty
• Hypercalcemia of Malignancy
• Osteoporosis
• Paget's Disease

Where can I get more information?

• Your pharmacist can provide more information about etidronate.

See also: Didronel side effects (in more detail)

Gen-Clindamycin

Gen-Clindamycin may be available in the countries listed below.

Ingredient matches for Gen-Clindamycin

Clindamycin

Clindamycin hydrochloride (a derivative of Clindamycin) is reported as an ingredient of Gen-Clindamycin in the following countries:

• Canada

International Drug Name Search